caspofungin

Term ID

CHEBI:474180

Synonyms

(10R,12S)-N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrr
(4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide
1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0
Caspofungin

Definition

A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.

References

Beilstein:8471798
CAS:162808-62-0
DrugBank:DB00520
Drug_Central:2977
KEGG:D07626
PMID:24270605
Patent:US5378804
Patent:WO9421677

Ontology

ChEBI ( EBI )

Relationships

is a type of: antibiotic antifungal drug echinocandin homodetic cyclic peptide semisynthetic derivative

antibiotic antifungal drug echinocandin homodetic cyclic peptide semisynthetic derivative Show first 5 Terms
has_functional_parent: pneumocandin B0

pneumocandin B0 Show first 5 Terms
has_role: antiinfective agent

antiinfective agent Show first 5 Terms
inverse has_part: caspofungin acetate

caspofungin acetate Show first 5 Terms

Phenotype

Phenotype resulting from caspofungin

Phenotype where environments contain caspofungin

Phenotype modified by environments containing caspofungin

Human Disease Model