TALEN

TALEN1-bmp8a

ID

ZDB-TALEN-220111-1

Name

TALEN1-bmp8a

Previous Names

None

Target

bmp8a (1)

Target Sequence 1

5' - TGGGCCTCGCTCTAAGC - 3'

Target Sequence 2

5' - TGACTAGCTCTGAAGAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ouc1002	bmp8a

Expression

Gene expression in Wild Types + TALEN1-bmp8a

No data available

Phenotype

Phenotype resulting from TALEN1-bmp8a

No data available

Phenotype of all Fish created by or utilizing TALEN1-bmp8a

Phenotype	Fish	Conditions	Figures
liver lipca expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue lpla expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue lipca expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
blood glucose increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue lepa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
blood triglyceride increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
blood cholesterol increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver visceral fat increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
adipose tissue ppargc1a expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver cel.1 expression increased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver lepa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver Ab2-ucp1 labeling decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
intestine cel.1 expression increased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
intestine cel.2 expression increased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue cholesterol increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
adipose tissue Ab5-smad labeling decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue Ab4-acaca labeling decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver adipoqb expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver pparab expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver ppargc1a expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver visceral fat dysplastic, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
liver ucp1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver cholesterol increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
whole organism increased mass, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
intestine Ab5-smad labeling increased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver cel.2 expression increased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver triglyceride increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
adipose tissue adipoqb expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue Ab2-ucp1 labeling decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver Ab4-acaca labeling decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue pparab expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
liver lpla expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue ucp1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 2 from Zhong et al., 2023
adipose tissue triglyceride increased amount, exacerbated	bmp8a^{ouc1002/ouc1002}	high fat	Fig. 1 from Zhong et al., 2023
kidney ifnphi1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
intestine ifnphi3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
intestine mxa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
spleen ifnphi3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
liver defense response to virus decreased efficacy, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 1 from Zhong et al., 2021
kidney ifnphi3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
liver ifnphi3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
spleen irf3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
kidney defense response to virus decreased efficacy, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 1 from Zhong et al., 2021
whole organism dead, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Sprivivirus cyprinus	Fig. 1 from Zhong et al., 2021
intestine tbk1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
liver irf7 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
spleen tbk1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
intestine irf3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
whole organism dead, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 1 from Zhong et al., 2021
spleen defense response to virus decreased efficacy, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 1 from Zhong et al., 2021
kidney mxa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
liver ifnphi1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
intestine defense response to virus decreased efficacy, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 1 from Zhong et al., 2021
kidney irf7 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
spleen mxa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
liver tbk1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
spleen irf7 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
liver irf3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
spleen ifnphi1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
liver mxa expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
intestine ifnphi1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 2 from Zhong et al., 2021
kidney irf3 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
kidney tbk1 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021
intestine irf7 expression decreased amount, abnormal	bmp8a^{ouc1002/ouc1002} (AB)	viral treatment by injection: Grass carp reovirus	Fig. 3 from Zhong et al., 2021

Citations