TALEN

TALEN1-grk1b

ID

ZDB-TALEN-190213-2

Name

TALEN1-grk1b

Previous Names

None

Target

grk1b (1)

Target Sequence 1

5' - TAGCAAGCTCAACCTGCCACAC - 3'

Target Sequence 2

5' - TATCCACTATAGTCTTCATTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nc201	grk1b

Expression

Gene expression in Wild Types + TALEN1-grk1b

No data available

Phenotype

Phenotype resulting from TALEN1-grk1b

No data available

Phenotype of all Fish created by or utilizing TALEN1-grk1b

Phenotype	Fish	Conditions	Figures
optomotor response decreased occurrence, abnormal	grk1b^nc201/nc201	standard conditions	Fig. 6 from Chrispell et al., 2018
eye Ab5-grk1 labeling increased amount, abnormal	grk1b^nc201/nc201	altered light dark cycle	Figure 6 from Chrispell et al., 2022
eye Ab5-grk1 labeling increased amount, abnormal	grk1b^nc201/nc201	altered light dark cycle, chemical treatment by environment: forskolin	Figure 6 from Chrispell et al., 2022
head Ab3-grk1 labeling decreased amount, abnormal	grk1b^nc201/nc201	standard conditions	Fig. 2 from Chrispell et al., 2018
retinal cone cell cone photoresponse recovery decreased occurrence, abnormal	grk1b^nc201/nc201	control	Fig. 4 from Chrispell et al., 2018
eye Ab5-grk1 labeling decreased amount, abnormal	grk1b^nc201/nc201	altered light dark cycle	Figure 5 from Chrispell et al., 2022
retinal cone cell cone photoresponse recovery delayed, abnormal	grk1b^nc201/nc201	control	Fig. 4 from Chrispell et al., 2018
retinal cone cell cone photoresponse recovery decreased process quality, abnormal	grk1b^nc201/nc201	chemical treatment by environment: (2S)-2-amino-4-phosphonobutanoic acid	Figure 4 from Chrispell et al., 2022
visual perception decreased process quality, abnormal	grk1b^nc201/nc201	standard conditions	Fig. 6 from Chrispell et al., 2018
eye cellular response to cAMP increased occurrence, abnormal	grk1b^nc201/nc201	altered light dark cycle, chemical treatment by environment: forskolin	Figure 6 from Chrispell et al., 2022
eye Ab5-grk1 labeling increased amount, abnormal	grk1b^nc201/nc201	chemical treatment by environment: forskolin	Figure 6 from Chrispell et al., 2022
retinal cone cell grk1b expression absent, abnormal	grk1b^nc201/nc201	standard conditions	Fig. 2 from Chrispell et al., 2018
retinal cone cell cone photoresponse recovery decreased process quality, exacerbated	grk1b^nc201/nc201	chemical treatment by environment: (2S)-2-amino-4-phosphonobutanoic acid, chemical treatment by environment: forskolin	Figure 4 from Chrispell et al., 2022
eye Ab3-grk1 labeling decreased amount, abnormal	grk1b^nc201/nc201	altered light dark cycle	Figure 5 from Chrispell et al., 2022

Citations