Gene

grk1b

ID
ZDB-GENE-050417-211
Name
G protein-coupled receptor kinase 1 b
Symbol
grk1b Nomenclature History
Previous Names
  • zgc:112194
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits rhodopsin kinase activity. Involved in cone photoresponse recovery. Is expressed in epiphysis; eye; retinal cone cell; and retinal photoreceptor layer.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Chrispell et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grk1b Human Ortholog
No data available
Associated With grk1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR016137 RGS domain
Family IPR000239 GPCR kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036305 RGS domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal GPCR kinase Protein kinase domain Protein kinase-like domain superfamily RGS domain RGS domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q567A3 559
UniProtKB:Q49HN0 559
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-grk1 monoclonal IgG1 Mouse
  • IHC
  • WB
Affinity BioReagents (Thermo Fisher Scientific)
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations