TALEN

TALEN2-irf8

ID

ZDB-TALEN-180524-1

Name

TALEN2-irf8

Previous Names

None

Target

irf8 (1)

Target Sequence 1

5' - ATGTTTCGAATCCCCT - 3'

Target Sequence 2

5' - CTTGATTGTAATCTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
cq47	irf8
cq48	irf8
hkz26	irf8

Expression

Gene expression in Wild Types + TALEN2-irf8

No data available

Phenotype

Phenotype resulting from TALEN2-irf8

No data available

Phenotype of all Fish created by or utilizing TALEN2-irf8

Phenotype	Fish	Conditions	Figures
common myeloid progenitor cebp1 expression increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
common myeloid progenitor spi1b expression increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
blood neutrophilic myelocyte increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 2 from Zhao et al., 2017
neutrophil mpx expression increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
neutrophil mpx expression increased distribution, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
common myeloid progenitor spi1b expression increased distribution, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
myeloid cell cell population proliferation increased occurrence, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
common myeloid progenitor cebp1 expression increased distribution, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
common myeloid progenitor cebpa expression increased distribution, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
blood neutrophilic metamyelocyte increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 2 from Zhao et al., 2017
common myeloid progenitor cebpa expression increased amount, abnormal	irf8^cq47/cq47 (AB)	standard conditions	Fig. 1 from Zhao et al., 2017
macrophage spi1b expression increased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
caudal hematopoietic tissue macrophage EGFP expression decreased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
trunk macrophage shape, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
trunk macrophage EGFP expression decreased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
macrophage spi1a expression increased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
brain microglial cell DsRedx expression decreased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
brain microglial cell ab3-lcp1 labeling decreased amount, abnormal	irf8^hkz26/hkz26; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017

Citations