TALEN

TALEN1-ezh2

ID

ZDB-TALEN-171114-1

Name

TALEN1-ezh2

Previous Names

None

Target

ezh2 (1)

Target Sequence 1

5' - CCTGTTTGCTGGAGGCGGCG - 3'

Target Sequence 2

5' - TGAGCTGCCGCAGCCGCATG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ul2	ezh2

Expression

Gene expression in Wild Types + TALEN1-ezh2

No data available

Phenotype

Phenotype resulting from TALEN1-ezh2

No data available

Phenotype of all Fish created by or utilizing TALEN1-ezh2

Phenotype	Fish	Conditions	Figures
exocrine pancreas decreased size, abnormal	ezh2^ul2/ul2	standard conditions	Fig. S4 from Dupret et al., 2017
trunk isl1a expression decreased amount, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 3 from Mingardo et al., 2024
pancreas cell apoptotic, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 4 from Dupret et al., 2017
whole organism decreased life span, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 7 from V�lkel et al., 2019 Fig. 4 from Dupret et al., 2017
spinal cord regeneration process quality, abnormal	ezh2^ul2/ul2	resection: spinal cord	Fig. 7 from Dupret et al., 2017
eye phox2bb expression mislocalised, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 5 from Dupret et al., 2017
apoptotic process increased occurrence, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 4 from Dupret et al., 2017
whole organism dead, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 4 from Dupret et al., 2017
pronephros isl1a expression decreased distribution, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 3 from Mingardo et al., 2024
histone methyltransferase activity decreased process quality, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 7 from Dupret et al., 2017
intestinal epithelium morphology, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 4 from Dupret et al., 2017
intestinal bulb epithelium morphology, abnormal	ezh2^ul2/ul2	standard conditions	Fig. S3 from Dupret et al., 2017
intestine cell apoptotic, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 4 from Dupret et al., 2017
exocrine pancreas prss1 expression decreased amount, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 6 from Dupret et al., 2017
exocrine pancreas development disrupted, abnormal	ezh2^ul2/ul2	standard conditions	Fig. 6 from Dupret et al., 2017
pronephric duct EGFP expression spatial pattern, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric duct malformed, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric duct EGFP expression decreased distribution, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric duct irregularly shaped, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric glomerulus EGFP expression decreased distribution, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric glomerulus Ab9-isl1 labeling decreased distribution, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
pronephric duct Ab9-isl1 labeling decreased distribution, abnormal	ezh2^ul2/ul2; li1Tg	standard conditions	Fig. 3 from Mingardo et al., 2024
whole organism decreased life span, exacerbated	ezh1^ul3/ul3; ezh2^ul2/ul2	standard conditions	Fig. 7 from V�lkel et al., 2019
whole organism decreased life span, abnormal	ezh1^ul3/ul3; ezh2^ul2/ul2	standard conditions	Fig. 7 from V�lkel et al., 2019

Citations