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ZIRC
ZFIN ID: ZDB-GENE-041111-259
Gene Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Gene Symbol: ezh2
Sequence Ontology ID : SO:0000704

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Previous Names: eya2, im:7149338, zgc:136376, zgc:152758

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have promoter-specific chromatin binding activity. Involved in several processes, including fin regeneration; histone H3-K27 methylation; and tissue homeostasis. Predicted to localize to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu5670 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1199 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1900 Point Mutation Unknown Splice Site ENU
    ul2 Indel Exon 2 Premature Stop TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH ezh2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Weaver syndrome Weaver syndrome 277590
    DISEASE ASSOCIATED WITH ezh2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive tract development (more)
    Cellular Component ESC/E(Z) complex (more)
    Molecular Function promoter-specific chromatin binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ezh2-201 (1) 3760
    ezh2-202 (1) 1255
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ezh2 No data available
    MARKER RELATIONSHIPS
    ezh2Contained in: [BAC] DKEY-117J14 (1) (order this)
    ezh2Encodes: [EST] IMAGE:7149338 (1) (order this)
    [cDNA] MGC:136376 (1) (order this), MGC:152758 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077279 (1) 3759bp
    Genomic GenBank:BX005392 (1) 178765bp
    Select Tool
    Polypeptide UniProtKB:A0A286Y9P9 (1) 770aa
    Sequence Clusters UniGene:76424 (1)
    Sequence Information (all 23)
    ORTHOLOGY for ezh2 (Chr: 24)
    CITATIONS (47)