TALEN

TALEN1-foxp3a

ID
ZDB-TALEN-170627-1
Name
TALEN1-foxp3a
Previous Names
None
Target
Target Sequence 1
5' - GCCAGTGGAAGTACA - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - AGCACTGATGGTCTG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
vcc6 foxp3a
Expression
Gene expression in Wild Types + TALEN1-foxp3a
No data available
Phenotype
Phenotype resulting from TALEN1-foxp3a
No data available
Phenotype of all Fish created by or utilizing TALEN1-foxp3a
Phenotype Fish Conditions Figures
whole organism il6 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
heart regeneration decreased efficacy, abnormal foxp3avcc6/vcc6 cold damage: heart Fig. S7 with image from Hui et al., 2017
whole organism il21 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism il22 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
regenerating tissue axon disorganized, abnormal foxp3avcc6/vcc6 transection: spinal cord Fig. S7 with image from Hui et al., 2017
gill inflamed, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
whole organism foxp3b expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. S4 from Sugimoto et al., 2017
whole organism cd4-1 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism lck expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism il4 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism ifng1r expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism pax5 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism mpeg1.1 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism eomesa expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism gata3 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
spinal cord regeneration decreased efficacy, abnormal foxp3avcc6/vcc6 transection: spinal cord Fig. S7 with image from Hui et al., 2017
pharynx inflamed, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
whole organism spi1b expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism il17a/f3 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism viability, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism decreased weight, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
T cell mediated immunity sensitivity of a process granuloma formation, abnormal foxp3avcc6/vcc6 bacterial treatment by injection: Mycobacteroides abscessus Fig. 6 with image from Kam et al., 2022
whole organism tnfa expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
intestine swollen, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
whole organism il26 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism decreased length, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
gill filament swollen, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
regenerating tissue Collagen increased amount, abnormal foxp3avcc6/vcc6 cold damage: heart Fig. S7 with image from Hui et al., 2017
olfactory epithelium inflamed, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
whole organism eomesb expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
integument inflamed, abnormal foxp3avcc6/vcc6 standard conditions Fig. 2 from Sugimoto et al., 2017
spinal cord axon regeneration process quality, abnormal foxp3avcc6/vcc6 transection: spinal cord Fig. S7 with image from Hui et al., 2017
regenerating tissue T cell increased amount, abnormal foxp3avcc6/vcc6 transection: spinal cord Fig. S7 with image from Hui et al., 2017
regenerating tissue retinal neural layer disorganized, abnormal foxp3avcc6/vcc6 perforation: retina Fig. S7 with image from Hui et al., 2017
whole organism cd8a expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
retina regeneration decreased efficacy, abnormal foxp3avcc6/vcc6 perforation: retina Fig. S7 with image from Hui et al., 2017
regenerating tissue Fibrin increased amount, abnormal foxp3avcc6/vcc6 cold damage: heart Fig. S7 with image from Hui et al., 2017
whole organism il1b expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
regenerating tissue T cell increased amount, abnormal foxp3avcc6/vcc6 cold damage: heart Fig. S7 with image from Hui et al., 2017
whole organism tbx21 expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
whole organism mpx expression increased amount, abnormal foxp3avcc6/vcc6 standard conditions Fig. 1 from Sugimoto et al., 2017
regenerating tissue T cell il10 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ transection: spinal cord Fig. 7 with image from Hui et al., 2017
regenerating tissue heart nrg1 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ cold damage: heart Fig. 7 with image from Hui et al., 2017
regenerating tissue cell population proliferation decreased occurrence, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell il10 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ cold damage: heart Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell igf1 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue spinal cord ntf3 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ transection: spinal cord Fig. 7 with image from Hui et al., 2017
regenerating tissue retina igf1 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue cardiac muscle cell proliferation decreased occurrence, abnormal foxp3avcc6/vcc6; vcc3Tg/+ cold damage: heart Fig. 7 with image from Hui et al., 2017
Muller cell cell population proliferation decreased occurrence, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell il10 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell nrg1 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ cold damage: heart Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell areg expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ perforation: retina Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell areg expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ cold damage: heart Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell ntf3 expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ transection: spinal cord Fig. 7 with image from Hui et al., 2017
regenerating tissue T cell areg expression decreased amount, abnormal foxp3avcc6/vcc6; vcc3Tg/+ transection: spinal cord Fig. 7 with image from Hui et al., 2017
regenerating tissue neuroblast proliferation decreased occurrence, abnormal foxp3avcc6/vcc6; vcc3Tg/+ transection: spinal cord Fig. 7 with image from Hui et al., 2017
intestine has extra parts of type T cell, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
integument T cell EGFP expression increased amount, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
pharynx T cell EGFP expression increased amount, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
intestine T cell EGFP expression increased amount, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
olfactory epithelium has extra parts of type T cell, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
gill has extra parts of type T cell, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
olfactory epithelium T cell EGFP expression increased amount, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
pharynx has extra parts of type T cell, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
integument has extra parts of type T cell, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
gill filament T cell EGFP expression increased amount, abnormal foxp3avcc6/vcc6; vcc4Tg/+ standard conditions Fig. 2 from Sugimoto et al., 2017
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.