TALEN

TALEN1-ccn2a

ID

ZDB-TALEN-161222-1

Name

TALEN1-ccn2a

Previous Names

TALEN1-ctgfa

Target

ccn2a (1)

Target Sequence 1

5' - GGAGAGTCTTTCCAG - 3'

Target Sequence 2

5' - CAGACACGTGCACTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
bns50	ccn2a

Expression

Gene expression in Wild Types + TALEN1-ccn2a

No data available

Phenotype

Phenotype resulting from TALEN1-ccn2a

No data available

Phenotype of all Fish created by or utilizing TALEN1-ccn2a

Phenotype	Fish	Conditions	Figures
intervertebral ligament shhb expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 from Rayrikar et al., 2022
regenerating tissue glial cell proliferation decreased amount, abnormal	ccn2a^bns50/bns50	transection: spinal cord	Fig. 2 from Mokalled et al., 2016
vertebral column ptch2 expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 from Rayrikar et al., 2022
intervertebral ligament fgfr1b expression increased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 4 from Rayrikar et al., 2022
spinal cord regeneration decreased process quality, abnormal	ccn2a^bns50/bns50	transection: spinal cord	Fig. 2 from Mokalled et al., 2016
intervertebral ligament shha expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 from Rayrikar et al., 2022
intervertebral ligament cell population proliferation decreased occurrence, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 , Fig. 5 from Rayrikar et al., 2022
regenerating tissue glial cell decreased amount, abnormal	ccn2a^bns50/bns50	transection: spinal cord	Fig. 2 from Mokalled et al., 2016
locomotory behavior decreased process quality, abnormal	ccn2a^bns50/bns50	transection: spinal cord	Fig. 2 from Mokalled et al., 2016
vertebral column fn1a expression increased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 2 from Rayrikar et al., 2022
vertebral column shha expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 4 from Rayrikar et al., 2022
spinal cord axon regeneration decreased occurrence, abnormal	ccn2a^bns50/bns50	transection: spinal cord	Fig. 2 from Mokalled et al., 2016
intervertebral ligament fused with intervertebral ligament, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 2 , Fig. 5 from Rayrikar et al., 2022
intervertebral ligament cell death increased occurrence, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 , Fig. 5 from Rayrikar et al., 2022
vertebral column curved, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 2 from Rayrikar et al., 2022
vertebral column fgfr1b expression increased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 4 from Rayrikar et al., 2022
intervertebral ligament fibronectin fibril organization increased occurrence, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 2 from Rayrikar et al., 2022
vertebral column gli1 expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 from Rayrikar et al., 2022
vertebral column ptch1 expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 3 from Rayrikar et al., 2022
vertebral column shhb expression decreased amount, abnormal	ccn2a^bns50/bns50	standard conditions	Fig. 4 from Rayrikar et al., 2022
intervertebral ligament fused with intervertebral ligament, ameliorated	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 5 from Rayrikar et al., 2022
vertebral column shha expression amount, ameliorated	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 4 from Rayrikar et al., 2022
intervertebral ligament cell death increased occurrence, ameliorated	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 5 from Rayrikar et al., 2022
vertebral column fgfr1b expression increased amount, abnormal	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 4 from Rayrikar et al., 2022
intervertebral ligament cell population proliferation decreased occurrence, ameliorated	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 5 from Rayrikar et al., 2022
vertebral column shhb expression amount, ameliorated	ccn2a^bns50/bns50; pd3Tg/pd3Tg	heat shock	Fig. 4 from Rayrikar et al., 2022

Citations