TALEN

TALEN1-prkdc

ID

ZDB-TALEN-161024-3

Name

TALEN1-prkdc

Previous Names

None

Target

prkdc (1)

Target Sequence 1

5' - TATGAATTTCTTAGGGGCAT - 3'

Target Sequence 2

5' - TCCTCGGACAGTGGCTGACA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genome Build: GRCz11Chromosome: 7

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
yu27	prkdc

Expression

Gene expression in Wild Types + TALEN1-prkdc

No data available

Phenotype

Phenotype resulting from TALEN1-prkdc

No data available

Phenotype of all Fish created by or utilizing TALEN1-prkdc

Phenotype	Fish	Conditions	Figures
developmental growth decreased process quality, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 2 from Jung et al., 2016
whole organism decreased length, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 2 from Jung et al., 2016
kidney decreased mass density, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 from Jung et al., 2016
monocyte increased amount, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Table 1 from Jung et al., 2016
whole organism neoplasm increased amount, abnormal	prkdc^yu27/yu27 (AB)	cancer xenotransplantation	Fig. 6 from Jung et al., 2016
immune response decreased process quality, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 2 from Jung et al., 2016
B cell activation arrested, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 5 from Jung et al., 2016
neutrophil increased amount, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Table 1 from Jung et al., 2016
kidney decreased thickness, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 from Jung et al., 2016
spleen decreased size, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 from Jung et al., 2016
thymus development decreased process quality, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 from Jung et al., 2016
kidney prkdc expression absent, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 1 from Jung et al., 2016
lymphocyte decreased amount, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 , Fig. 4 , Table 1, Table 2 from Jung et al., 2016
T cell receptor V(D)J recombination arrested, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 5 from Jung et al., 2016
immunoglobulin heavy chain V-D-J recombination arrested, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 5 from Jung et al., 2016
T cell activation arrested, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 5 from Jung et al., 2016
spleen prkdc expression absent, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 1 from Jung et al., 2016
whole organism neoplastic, abnormal	prkdc^yu27/yu27 (AB)	cancer xenotransplantation	Fig. 6 from Jung et al., 2016
thymus rag1 expression decreased amount, abnormal	prkdc^yu27/yu27 (AB)	standard conditions	Fig. 3 from Jung et al., 2016

Citations

Include unpublished citations

Jung, I.H., Chung, Y.Y., Jung, D.E., Kim, Y.J., Kim, d.o. .H., Kim, K.S., Park, S.W. (2016) Impaired Lymphocytes Development and Xenotransplantation of Gastrointestinal Tumor Cells in Prkdc-Null SCID Zebrafish Model. Neoplasia (New York, N.Y.). 18:468-79

1 - 1 of 1

Show