ZFIN ID: ZDB-FISH-171005-7
Fish name: prkdcyu27/yu27
Genotype: prkdcyu27/yu27 (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by prkdcyu27/yu27
Human Disease Conditions Citations
severe combined immunodeficiency standard conditions Jung et al., 2016
GENE EXPRESSION
Gene expression in prkdcyu27/yu27
Reporter gene expression No data available
PHENOTYPE
Phenotype in prkdcyu27/yu27
Phenotype Conditions Figures
B cell activation arrested, abnormal standard conditions Fig. 5 with image from Jung et al., 2016
developmental growth decreased process quality, abnormal standard conditions Fig. 2 with image from Jung et al., 2016
immune response decreased process quality, abnormal standard conditions Fig. 2 with image from Jung et al., 2016
immunoglobulin heavy chain V-D-J recombination arrested, abnormal standard conditions Fig. 5 with image from Jung et al., 2016
kidney prkdc expression absent, abnormal standard conditions Fig. 1 from Jung et al., 2016
kidney decreased mass density, abnormal standard conditions Fig. 3 with image from Jung et al., 2016
kidney decreased thickness, abnormal standard conditions Fig. 3 with image from Jung et al., 2016
lymphocyte decreased amount, abnormal standard conditions Fig. 3 with imageFig. 4 with imageTable 1Table 2 from Jung et al., 2016
monocyte increased amount, abnormal standard conditions Table 1 from Jung et al., 2016
natural killer cell present, normal standard conditions Fig. 5 with image from Jung et al., 2016
neutrophil increased amount, abnormal standard conditions Table 1 from Jung et al., 2016
spleen prkdc expression absent, abnormal standard conditions Fig. 1 from Jung et al., 2016
spleen decreased size, abnormal standard conditions Fig. 3 with image from Jung et al., 2016
T cell activation arrested, abnormal standard conditions Fig. 5 with image from Jung et al., 2016
T cell receptor V(D)J recombination arrested, abnormal standard conditions Fig. 5 with image from Jung et al., 2016
thymus rag1 expression decreased amount, abnormal standard conditions Fig. 3 with image from Jung et al., 2016
thymus development decreased process quality, abnormal standard conditions Fig. 3 with image from Jung et al., 2016
whole organism decreased length, abnormal standard conditions Fig. 2 with image from Jung et al., 2016
whole organism length, normal standard conditions Fig. 2 with image from Jung et al., 2016
whole organism neoplastic, abnormal cancer xenotransplantation Fig. 6 with image from Jung et al., 2016
whole organism neoplasm increased amount, abnormal cancer xenotransplantation Fig. 6 with image from Jung et al., 2016

CITATIONS  (1)