Morpholino
MO2-stx1b
- ID
- ZDB-MRPHLNO-150212-9
- Name
- MO2-stx1b
- Previous Names
- None
- Target
- Sequence
-
5' - AAATATCTCTTGAGATGTCCGCTGC - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Translation-blocking MO, targets the 5'UTR.
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-stx1b
Expressed Gene | Anatomy | Figures |
---|---|---|
fosab |
Fig. 3 ![]() ![]() |
|
stx1b |
Fig. 3 ![]() ![]() |
Phenotype
Phenotype resulting from MO2-stx1b
Phenotype of all Fish created by or utilizing MO2-stx1b
Citations
- Zheng, Y.M., Chen, B., Jiang, J.D., Zhang, J.P. (2018) Syntaxin 1B Mediates Berberine's Roles in Epilepsy-Like Behavior in a Pentylenetetrazole-Induced Seizure Zebrafish Model. Frontiers in molecular neuroscience. 11:378
- Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J.R., de Kovel, C.G., Thiele, H., Konrad, K., Kawalia, A., Toliat, M.R., Sander, T., Rüschendorf, F., Caliebe, A., Nagel, I., Kohl, B., Kecskés, A., Jacmin, M., Hardies, K., Weckhuysen, S., Riesch, E., Dorn, T., Brilstra, E.H., Baulac, S., Møller, R.S., Hjalgrim, H., Koeleman, B.P., EuroEPINOMICS RES Consortium, Jurkat-Rott, K., Lehman-Horn, F., Roach, J.C., Glusman, G., Hood, L., Galas, D.J., Martin, B., de Witte, P.A., Biskup, S., De Jonghe, P., Helbig, I., Balling, R., Nürnberg, P., Crawford, A.D., Esguerra, C.V., Weber, Y.G., Lerche, H. (2014) Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nature Genetics. 46(12):1327-32
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