Gene

stx1b

ID
ZDB-GENE-000330-4
Name
syntaxin 1B
Symbol
stx1b Nomenclature History
Previous Names
  • fb76h10
  • syntaxin1b
  • wu:fb76h10
  • zgc:92909
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have SNAP receptor activity and SNARE binding activity. Involved in regulation of synaptic activity. Predicted to localize to several cellular components, including SNARE complex; endomembrane system; and integral component of membrane. Used to study epilepsy. Human ortholog(s) of this gene implicated in generalized epilepsy with febrile seizures plus 9. Is expressed in nervous system and trigeminal placode. Orthologous to human STX1B (syntaxin 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With stx1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
generalized epilepsy with febrile seizures plus 9 Alliance Generalized epilepsy with febrile seizures plus, type 9 616172
Associated With stx1b Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006012 Syntaxin/epimorphin, conserved site
Domain IPR000727 Target SNARE coiled-coil homology domain
Domain IPR006011 Syntaxin, N-terminal domain
Family IPR028669 Syntaxin 1
Family IPR045242 Syntaxin
Homologous_superfamily IPR010989 SNARE
Domain Details Per Protein
Protein Length SNARE Syntaxin Syntaxin 1 Syntaxin/epimorphin, conserved site Syntaxin, N-terminal domain Target SNARE coiled-coil homology domain
UniProtKB:A0A286Y9I3 281
UniProtKB:Q6DGI4 224
UniProtKB:Q1MTI1 288
UniProtKB:Q9I9P6 288
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations