Gene

cdon

ID
ZDB-GENE-021115-4
Name
cell adhesion associated, oncogene regulated
Symbol
cdon Nomenclature History
Previous Names
  • cb507 (1)
  • wu:fa10c03
  • wu:fb94b11
  • zgc:158240
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Involved in negative regulation of smoothened signaling pathway. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including immature eye; mesoderm; nervous system; neural tube; and pectoral fin. Human ortholog(s) of this gene implicated in holoprosencephaly 11. Orthologous to human CDON (cell adhesion associated, oncogene regulated).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Cardozo et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdon Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
holoprosencephaly 11 Alliance Holoprosencephaly 11 614226
Associated With cdon Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013106 Immunoglobulin V-set domain
Family IPR032983 Cell adhesion molecule-related/down-regulated by oncogenes
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Cell adhesion molecule-related/down-regulated by oncogenes Fibronectin type III Fibronectin type III superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Immunoglobulin V-set domain
UniProtKB:A4JYJ4 349
UniProtKB:Q1L8D0 1125
UniProtKB:A0A0B5JK41 825
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations