| 
            Phenotype
         | 
            
                Fish
             | 
            
                Conditions
             | 
        
            Figures
         | 
    
    
    
        
            | 
                skeletal muscle neuromuscular junction morphology, abnormal
             | 
                
                    AB + MO1-dag1 + MO2-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Bailey et al., 2019 
                
             | 
        
    
        
            | 
                skeletal muscle neuromuscular junction morphology, abnormal
             | 
                
                    AB + MO1-dag1 + MO2-dag1
                 | 
                
                    chemical treatment by environment: NAD
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Bailey et al., 2019 
                
             | 
        
    
        
            | 
                embryo development delayed, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                caudal fin kinked, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5
                    
                    from Moore et al., 2008 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction malformed, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 1  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum malformed, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 1  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum basement membrane irregular spatial pattern, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                musculoskeletal movement disrupted, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                post-vent region muscle cell morphology, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5
                    
                    from Lefebvre et al., 2007 
                
             | 
        
    
        
            | 
                muscle disorganized, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                muscle necrotic, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                post-vent region increased curvature, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                muscle sarcomere morphology, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                myotome basement membrane morphology, ameliorated
             | 
                
                    WT + MO1-dag1
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                locomotion involved in locomotory behavior decreased rate, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 8  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                muscle sarcomere decreased amount, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                myoseptum broken, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Goody et al., 2010 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction disorganized, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 1  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                muscle sarcoplasmic reticulum unstructured, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                myotome muscle cell detached from myotome muscle tendon junction, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  , 
                    
                        Fig. 6  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                whole organism dystrophic, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                ventral fin fold decreased size, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Parsons et al., 2002 
                
             | 
        
    
        
            | 
                muscle attachment disrupted, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. S2  
                    
                    from Postel et al., 2008 
                
             | 
        
    
        
            | 
                locomotion involved in locomotory behavior decreased rate, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 8  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                trunk musculature skeletal muscle cell retracted, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. S2  
                    
                    from Postel et al., 2008 
                
             | 
        
    
        
            | 
                myotome muscle cell attached to myotome muscle tendon junction, ameliorated
             | 
                
                    WT + MO1-dag1
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome basement membrane malformed, abnormal
             | 
                
                    WT + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                embryo development delayed, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                somite intersegmental vessel absent, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                larval locomotory behavior disrupted, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                somite myoseptum deformed, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 4
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                somite intersegmental vessel disorganized, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                whole organism dead, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                post-vent region decreased length, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 2
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                dorsal aorta intersegmental vessel separated from dorsal longitudinal anastomotic vessel, abnormal
             | 
                
                    y1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5
                    
                    from Wood et al., 2011 
                
             | 
        
    
        
            | 
                post-vent region skeletal muscle cell retracted, abnormal
             | 
                
                    ilkhu801/hu801 + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 1  
                    
                    from Postel et al., 2008 
                
             | 
        
    
        
            | 
                muscle attachment disrupted, abnormal
             | 
                
                    ilkhu801/hu801 + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 1  
                    
                    from Postel et al., 2008 
                
             | 
        
    
        
            | 
                receptor clustering disrupted, abnormal
             | 
                
                    musktbr307/tbr307 + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 3
                    
                    from Lefebvre et al., 2007 
                
             | 
        
    
        
            | 
                skeletal muscle cell detached from vertical myoseptum, abnormal
             | 
                
                    AB/TU + MO1-dag1 + MO1-lama2
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Charvet et al., 2013 
                
             | 
        
    
        
            | 
                muscle attachment decreased process quality, abnormal
             | 
                
                    AB/TU + MO1-dag1 + MO1-lama2
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Charvet et al., 2013 
                
             | 
        
    
        
            | 
                myotome muscle cell degenerate, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum U-shaped, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction U-shaped, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum U-shaped, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction U-shaped, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell degenerate, abnormal
             | 
                
                    WT + MO1-dag1 + MO1-itga6a + MO2-itga6a
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 5  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell degenerate, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction malformed, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell detached from myotome muscle tendon junction, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell degenerate, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum malformed, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell detached from myotome muscle tendon junction, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                vertical myoseptum malformed, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    chemical treatment: NAD(+)
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle tendon junction malformed, abnormal
             | 
                
                    WT + MO1-dag1 + MO2-itga7
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 3  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                locomotion involved in locomotory behavior decreased rate, abnormal
             | 
                
                    mai1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 8  
                    
                    from Goody et al., 2012 
                
             | 
        
    
        
            | 
                myotome muscle cell detached from myotome muscle tendon junction, abnormal
             | 
                
                    mai1Tg + MO1-dag1
                 | 
                
                    standard conditions
                 | 
            
                
                    
                        Fig. 6  
                    
                    from Goody et al., 2012 
                
             |