IMAGE

Figure 3.

ID

ZDB-IMAGE-260413-22

Genes

col4a6

Publication

Owrang et al., 2025 - Uncovering Dual Molecular Diagnoses in Families with Complex Phenotypes through Structural and Clinical Study of Novel COL4A6 Variants

All Figures

Figures for Owrang et al., 2025

Image

Figure Caption

Figure 3.

Spatial and temporal expression pattern of col4a6 mRNA during zebrafish development. (A) At 1 day post-fertilization (dpf), col4a6 mRNA is expressed in the epidermis, otic vesicles (Ov), and midbrain-hindbrain boundary (MHB), where the epidermis is enlarged for clarity as shown in A″. Panel A′ shows a dorsal view of panel A with a flattened mount. (B) At 2 dpf, col4a6 mRNA is persistently expressed in the MHB, ear (enlarged in B″), and epidermis, and is beginning to be expressed in the pharyngeal arch (Pa) and pectoral fin bud (Pb). (C) At 3 dpf, col4a6 mRNA is persistently expressed in the pharyngeal arch and ear (enlarged in C′) and becomes restricted in the dorsal dermis (Dd, enlarged in C″). In addition, col4a6 mRNA is expressed in the pronephric duct (Pnd). (D) At 5 dpf, col4a6 mRNA is persistently expressed in the pharyngeal arch and ear (enlarged in D′ and dorsal view in D″), with additional expression in the intestinal bulb (IB) and cloaca (Cl). Unlabeled scale bars are 0.3 mm.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ QJM