Gene
col4a6
- ID
- ZDB-GENE-101001-2
- Name
- collagen, type IV, alpha 6
- Symbol
- col4a6 Nomenclature History
- Previous Names
-
- im:7147757
- shiomaneki (1)
- sio
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have extracellular matrix structural constituent. Involved in axon extension involved in axon guidance and basement membrane organization. Predicted to localize to collagen type IV trimer and extracellular space. Human ortholog(s) of this gene implicated in X-linked deafness 6. Is expressed in several structures, including head; hypodermis; otic vesicle; swim bladder; and swim bladder bud. Orthologous to human COL4A6 (collagen type IV alpha 6 chain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147757 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked deafness 6 | Alliance | ?Deafness, X-linked 6 | 300914 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Collagen IV, non-collagenous | Collagen IV, non-collagenous domain superfamily | Collagen superfamily | Collagen triple helix repeat | C-type lectin fold |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QD06
|
1688 | |||||
|
UniProtKB:A0A8M3B4D5
|
1686 | |||||
|
UniProtKB:A0A8M6Z091
|
1714 | |||||
|
UniProtKB:A0A8M6Z7E0
|
1717 | |||||
|
UniProtKB:A0A8M6Z1T7
|
1700 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
col4a6-201
(1)
|
Ensembl | 5,145 nt | ||
| mRNA |
col4a6-202
(1)
|
Ensembl | 8,255 nt | ||
| mRNA |
col4a6-203
(1)
|
Ensembl | 5,001 nt |
Interactions and Pathways
No data available
Plasmids
No data available