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Fig. 6

ID
ZDB-IMAGE-250916-27
Source
Figures for Stefan et al., 2025
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Figure Caption

Fig. 6 Structural analyses of human OATP1B1 (PDB IDs 8HNC, 8HND, 8HNH, and 8K6L) and colocalized ligands (A), i.e., bilirubin (BIL; B), 2′,7′-dichlorofluorescein (DCF; C), the pan-SLC transporter modulator estrone sulfate (EST; D), and simeprevir (SIM; E). Additionally shown is the AlphaFold 3-generated [43] structure of drOatp1d1 (UniProt entry A0A8M9PU70; F) with blindly-docked molecules, i.e., BEN (G), DIP (H), MK (I), PRA (J), and BSP (K).

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