Comparison of startle reflex in zebrafish larvae at 6 days post-fertilization. a Bar graph depicting the latency (time from stimulus application to the onset of movement) across the control, RFP control, HOMER2 WT, HOMER2 p.R345*, and HOMER2 p.R345Efs*64 groups. The latency was significantly longer in the HOMER2 p.R345Efs*64 group compared to HOMER2 WT (p < 0.05). b Bar graph showing the distance moved during the startle response. The HOMER2 p.R345Efs*64 groups exhibited a significant reduction in distance moved compared to HOMER2 WT and p.R345*, and showed a further reduction relative to the RFP control group (p < 0.05). n = 20 per group. RFP, red fluorescent protein; WT, wild-type; R, arginine; E, glutamate; fs, frameshift
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Full text @ J. Mol. Med.
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