ZFIN Image: Chen et al., 2025, Figure 5

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Figure Caption

Figure 5

Haploinsufficiency of Kdm6a dysregulates aging related gene expression in HSPCs. A) Flowchart of sorting and RNA sequencing. B) Heatmap of differentially expressed genes in HSPCs from kdm6a^+/− mutants and their WT controls at 3 dpf via RNA‐seq (cut‐off fold change 1.5, p < 0.05). C) Gene ontology (GO) enrichment analysis of biological processes based on differentially expressed genes identified through RNA‐seq. D) Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis based on differentially expressed genes identified through RNA‐seq. E) Gene set enrichment analysis (GESA) of RNA expression profiles in HSPCs from kdm6a^+/− mutants and their WT controls at 3 dpf.

Acknowledgments

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