ZFIN Image: Shin et al., 2025, Fig. 2

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Figure Caption

Fig. 2

Electrical hyperexcitability in napb CR. Neural activity and neural network were monitored using MEA. (A) Inverted microscope image of a control zebrafish larva, laterally immobilized on the electrodes of MEA plates. (B) Heat map of spontaneous spike amplitude (µV) of a control zebrafish, showing that detected extracellular activity aligns with the zebrafish’s orientation (white dot). The red circle indicates the head region. (C) Well-wide raster plot illustrating synchronized spinal cord and brain neural activity in the control zebrafish. The red dotted line indicates neural activity in the brain region. (D-F) Hyperactive neural activity of napb CR. (D, E) Heat map of spontaneous spike amplitude (µV) and (F) raster plot of napb CR. (G) The number of zebrafish larvae exhibiting hyperactive neural activity in the brain region; control (n = 21) and napb CR (n = 21).

Acknowledgments

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