ZFIN Image: Le et al., 2025, FIGURE 10

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Figure Caption

FIGURE 10

c1q levels measured by RT-qPCR in control and crim1^−/− larvae that are homozygous for a 2 base pair deletion, c.339_340delCT p.Leu112Leufs*3, at 72 h post fertilization (hpf). RT-qPCR showing expression of c1qa, c1qb, c1qc, cd74a, and cd74b in crim1^−/− larvae compared to controls. RT-qPCR was performed on dissected eyes for all experiments from control (white columns; expression normalized to 1.0) and crim1^−/− larvae (black columns) at 72 hpf. The results show significantly increased expression of c1qb (P = 0.018) and significantly reduced expression of c1qc (P = 0.003) and cd74b (P = 0.032) in crim1^−/− larvae compared to controls. c1qa (P = 0.154) and cd74a (P = 0.391) expression was not significantly different.

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Acknowledgments

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