ZFIN Image: Zhang et al., 2024, Fig. 1

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Figure Caption

Fig. 1 IC50 values of GPCR-acting pharmaceuticals against human (hD2, hβ1, and hH1) and zebrafish (zD2a, zD2c, zβ1, and zH1) receptors. Plots indicate the mean IC50 values (M) of GPCR-acting pharmaceuticals measured in the present study. Red (zD2a, zβ1, and zH1) and blue (zD2c) plots are IC50 values for zebrafish GPCRs, and black plots indicate IC50 values for zebrafish GPCRs (hD2, hβ1, and hH1). Red open circle indicates that the IC50 was >10–5 M; atenolol against zβ1 receptor did not reach 50% AP-TGFα release in the tested concentration range (10–10 to 10–5 M). The IC50 values of GPCR-acting pharmaceuticals against human GPCRs (hD2, hβ1, and hH1) were cited from our previous study. (28)

Acknowledgments

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