ZFIN Image: Wawruszak et al., 2025, Figure 6.

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Figure Caption

Figure 6.

In vivo experiments with zebrafish xenografted model. (a) Drug screening scheme with zebrafish larvae model. (b) The impact of 1/8 IC₅₀ EX527, PAX and the combination of both compounds (1/8 IC_{50 mix}) on T47D xenografted zebrafish model after 3 days of treatment. The representative images of Vybrant^™ DiD-stained tumour cells after treatment were illustrated. (c) Relative expression of human GAPDH versus zebrafish gapdh in zebrafish larvae after 1/8 IC₅₀ EX527, PAX and EX527:PAX (1/8 IC_{50 mix}) treatment. Data are presented as mean ± standard deviation of the mean (SD), ***p < 0.001 determined by one-way ANOVA, Tukey’s post-hoc test.

Acknowledgments

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