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Figure Caption
Fig. 2 Overlay of compound 3 with the structure-based pharmacophore model derived from the most representative molecular dynamics binding mode of inhibitor in the C-terminal domain binding site of the Hsp90? dimer [28] (PDB entry: 5FWK). Blue star represents a positively ionizable pharmacophore feature, green arrow a hydrogen bond donor pharmacophore feature, yellow spheres hydrophobic pharmacophore feature and grey spheres represent excluded volumes.
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