IMAGE

Fig. 1

ID: ZDB-IMAGE-241212-43
Publication: Zhu et al., 2024 - Allelic heterogeneity of TTNtv cardiomyopathy can be modeled in adult zebrafish
All Figures: Figures for Zhu et al., 2024

Image

Figure Caption

Fig. 1 AH in cardiac function and sarcomere structure is noted in homozygous ttntv embryos. (A) Schematics of the ttntv mutants. These mutants have been generated previously (33). * indicates the location of truncation mutations. (B) Quantification of fractional shortening in the embryonic hearts at 2 dpf. *P < 0.0001. (C) Quantification of fractional shortening in the embryonic hearts at 9 dpf. (D) Comparison of cardiac sarcomere structure in 2 dpf embryos via F59 antibody staining. Scale bar = 20 μm. Insets show enlarged images of the area enclosed with dashed lines. Scale bar = 5 μm. Arrowheads indicate sarcomeres with striated patterns. Arrows indicate immature sarcomeres with less striated patterns.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ JCI Insight