ZFIN Image: Wei et al., 2024, Figure 6

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Figure Caption

Figure 6

Ethacrynic acid causes less damage to normal hematopoiesis than ATRA. (A) DIC images of zebrafish WT embryos at 3 and 4 dpf after treatment with ATRA (0.1 μM) and ethacrynic acid (20 μM) at 24 hpf. (B) WISH of cmyb, mpx, and rag1 in WT embryos at 3 and 4 dpf after treatment with ATRA and ethacrynic acid at 24 hpf. A green arrow indicates the staining signal. (C) SB and NR staining of WT embryos at 4 dpf after chemical treatment. Results are represented as mean ± SEM, n = 3, t-test; *** p < 0.001, **** p < 0.0001; ns, not significant. (D) Benzidine staining of WT embryos at 4 dpf after chemical treatment. SB, Sudan black; NR, neutral red.

Acknowledgments

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