ZFIN Image: Schneegans et al., 2024, Fig. 5

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Figure Caption

Fig. 5

HERC5 induces changes in mitochondrial morphology. A Representative electron microscopy images of A549 PAR/KO and HTB56 OE/EC cells. B Mitochondrial density and size increase in cells with high HERC5 expression (density: HTB56 EC/OE: p = 0.001; A549 KO/PAR: p < 0.0001; n = 30; size: HTB56 EC/OE: p < 0.0001, n = 490/578; A549 KO/PAR: p < 0.0001, n = 337/395; Student’s T-test). C HTB56 EC and A549 HERC5 KO have a decreased NAD/NADH ratio compared to HTB56 HERC5 OE (p = 0.003, n = 3, Student’s T-test) and A549 PAR (p = 0.017, n = 3, Student’s T-test) cells, respectively. Error bars in bar plots are depicting the standard deviation

Acknowledgments

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