IMAGE

FIGURE 5

ID

ZDB-IMAGE-240124-43

Genes

bglap
sp7

Publication

Ramli et al., 2024 - Piezo1 mutant zebrafish as a model of idiopathic scoliosis

All Figures

Figures for Ramli et al., 2024

Image

Figure Caption

FIGURE 5

Abnormal osteoblast function. (A,B) Representative image of alkaline phosphatase staining in vertebral bone section of wildtype (N = 4) and piezo1^{11aa del/11aa del} (N = 5). Red boxes indicate the magnified area of growth plate. Blue arrow indicates center of growth plate, orange arrow indicates growth plate at the opposite site. Scale bar is 100 μm. (C) Fluorescence images of vertebral bone of wildtype; (osx-GFP) and piezo1^{11aa del/11aa del}; (osx-GFP) at 25 dpf. (D) Quantitative analysis of fluorescence area. Values are presented as mean ± SD and analyzed using Student’s t-test. ***p < 0.001. mRNA level of(E) osterix, mid-stage osteoblast marker gene, and(F) osteoclacin/bglap, late-stage osteoblast marker gene. Values are presented as mean ± SD and analyzed using Student’s t-test. ****p < 0.0001.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet