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Figure 6

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ZDB-IMAGE-231116-48
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Figures for Taler et al., 2023
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Figure 6

Effects of 4-PBA treatment on TGFβ and EGFR signaling. (AD) Confocal single-plane sections from eyes of plod3vu222 mutants untreated (A,C) or treated with 4-PBA (B,D) from ~26 hpf. In (A,B), treatment was until ~96 hpf and sections were labeled for pSmad3 (red) and nuclei (Dapi, blue). In (C,D), treatment was until 76 hpf and sections were labeled for pERK1/2 (red) and nuclei (Dapi, blue). Asterisk in (A) marks the area of the cell mass where pSmad3 labeling is evident. Arrowheads in (B,D) point at the ALE. White line in (C) marks the periphery of the cell mass. L, lens. Scale bars are 20 µm.

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