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Figure 2
(A) The indicated cell lines were treated (in independent experiments, performed in triplicate) with different doses of cabozantinib (µM), for the indicated times. Distribution of cells in the different phases of cell cycle was measured by propidium iodide. (B) BON1 cells were stained for DNA content: arrows point to cells arrested during mitosis in a polynucleated state. A full-colour version of this figure can be found at
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