ZFIN Image: Domingues et al., 2023, Fig. 3

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Fig. 3

ChA affects the cytokine profile of neutrophils. Neutrophils were harvested from human volunteers (five different donors) using a gradient with histopaque-1177 and 1009. Cells were cultured in the presence of ChA (25, 100, and 500 μM) or vehicle for 4 h. After treatment, neutrophils were stained with monoclonal antibodies to determine the expression of CD11b (A) and cytokines: IL-1β (B), TNF-α (C), IL-6 (D), and IL-10 (E); data represent the percentage of positive cells for each inflammatory marker normalized to the control cells. ∗P < 0.05; ∗∗P < 0.01 using one-way ANOVA with Dunnett’s multiple comparisons test.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Lipid Res.