FLVCR1a expression is enhanced in angiogenic endothelial cells (aECs). A qRT-PCR analysis showing Flvcr1a mRNA levels in wild-type mouse embryos at different developmental stages (i.e., embryonic day (E) 9.5, 11.5, E13.5, E15.5). n = 4. B qRT-PCR analysis showing Flvcr1a transcript levels in embryonic ECs (CD31+) and non-endothelial fractions (CD31−) collected from mouse embryos at E9.5 and E13.5. n = 3. C qRT-PCR analysis showing Flvcr1a mRNA levels in embryonic angiogenic ECs (E9.5) and tumor-associated ECs (TECs) from Lewis Lung Carcinoma Cells (LLC)-xenografts. D qRT-PCR analysis showing Flvcr1a transcript levels in mouse ECs isolated from adult lung and LLC tumors. E, F Representative Western Blot analysis (E) and quantification (F) of FLVCR1a-myc-tagged protein expression in murine ECs from adult lung and LLC tumor. GFLVCR1a expression levels in human qECs (capillary ECs) and aECs (immature/stalk and tip cells) isolated from lung adenocarcinoma. Data were taken from public available database. aECs angiogenic ECs, NEC/TEC Normal/Tumor ECs, RQ Relative Quantification. Data are representative of at least 3 independent experiments and are expressed as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. For statistical analyses, ordinary one-way ANOVA test with Tukey’s multiple comparisons (A, B), parametric unpaired t test (C, D, F), and Mann–Whitney test (G) were used
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Angiogenesis
Your Input Welcome
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if
additional information is required.
Oops. Something went wrong. Please try again later.