IMAGE

Figure 8

ID
ZDB-IMAGE-230518-120
Source
Figures for Parameswaran et al., 2023
Image
Figure Caption

Figure 8

Proposed pathogenic mechanisms caused by C9ORF72 antisense C4G2 repeat expanded RNAs.

C9ORF72 antisense C4G2 repeat expanded RNAs activate PKR/eIF2α-dependent integrated stress response and lead to neurotoxicity independent of DPR proteins.

Acknowledgments
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