Figure 5 Changes in cell cycle phase distribution of MDA-MB-231 cells upon treatment with compounds 6b, 7b, 8b, 9b, and tubastatin A. After the 24 h, 48 h, and 72 h continual treatment of MDA-MB-231 cells with investigated compounds at IC50, as well as tubastatin A at IC50 and 20 μM, cells were stained with propidium iodide and analyzed by flow cytometry. White bar—apoptotic cells with DNA content corresponding to sub-G1 fraction; sandy bar—cells with DNA content corresponding to G0/G1 phases; orange bar—cells with DNA content corresponding to S phase; maroon bar—cells with DNA content corresponding to G2/M phases (compared to the untreated control).
Image
Figure Caption
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Pharmaceutics