ZFIN Image: Zhang et al., 2021, Fig. 2

Image

Figure Caption

Fig. 2 Transcytosis of ZpD and ZpD-G23 NPs across an in vitro BBB model. Distribution of coumarin-6 and coumarin-6 labeled ZpD and ZpD-G23 NPs in the filter-free BBB model after incubation (at an equal concentration of 1 μg mL⁻¹ coumarin-6) for 2 (A), 4 (B) and 8 (C) hours at 37 °C (n = 3 in duplicate). Basolateral fluorescence signal represents fraction that crossed the BBB. (D) Basolateral fluorescence signal after incubation of the BBB model with coumarin-6 and coumarin-6 labeled ZpD and ZpD-G23 NPs for 2, 4, and 8 hours. *Significantly different from free coumarin-6; ^# significantly different from Coumarin6-ZpD NPs, P < 0.05.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomater Sci