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Feng et al., 2022 - The Polycomb group gene rnf2 is essential for central and enteric neural system development in zebrafish

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FIGURE 5

The effect of rnf2 deficiency on differentiation of neural crest in zebrafish embryos. (A) The expression of cxcr4a in rnf2^–/– and WT embryos at 12 hpf. Upper: lateral view, bottom: dorsal view. (B) The expression of vgll2a in rnf2^–/– and WT embryos at 12 hpf. Upper: lateral view, bottom: dorsal view. (C) The expression of prdm1a in rnf2^–/– and WT embryos at 12 hpf. Upper: lateral view; middle: dorsal anterior view; bottom: dorsal posterior view. Red arrows showing the expression of cxcr4a, vgll2a, and prdm1a in 12 hpf WT embryos, black arrows showing the reduced expression of cxcr4a, vgll2a, and prdm1a in 12 hpf rnf2^–/– mutant embryos. The experiments were repeated at least three times. Scale bar = 0.1 mm.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Neurosci.