IMAGE

Fig. 2

ID: ZDB-IMAGE-220906-13
Publication: Toh et al., 2022 - Optogenetic control of YAP cellular localisation and function
All Figures: Figures for Toh et al., 2022

Image

Figure Caption

Fig. 2

Figure 2. Light activation of optoYAP can activate downstream YAP target genes and control cell proliferation

A. Expression levels of ANKRD1, CTGF, and CYR61 transcripts in HEK293T cells transfected with optoYAP after 48 h of activation protocol. Gene expression level was normalised to the housekeeping gene, EIF1B. Horizontal bars represent mean and 95% confidence interval from six biological replicates across two independent experiments for each condition, ***P < 10⁻³ (unpaired t-test).
B, C. Cell proliferation assay. HEK293T (B) and HFF (C) cells were transfected with optoYAP and subjected to activation protocol as described in Fig 1A or kept in the dark for 1 week. Error bars are s.d., n = 3 independent experiments for each condition, **P < 10⁻² (unpaired t-test).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Rep.