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Fig 7

ID: ZDB-IMAGE-210623-68
Publication: Swartz et al., 2021 - Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling
All Figures: Figures for Swartz et al., 2021

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Figure Caption

Fig 7 Gata3 functions downstream of Bmp in palate development.

(A-C) Flat mounts of 4 dpf neurocrania anterior to the left. (A) Wild type phenotype of the hsp:DN-BmpR1a with no heat shock. (B) Severely affected trabeculae typical of the hsp:DN-BmpR1a when heat shocked at 24 hpf. (C) A typical rescue of the hsp:DN-BmpR1a;hsp:GATA3-EGFP heat shock phenotype at 24 hpf. (D) Graph depicting quantification of heat shock phenotype scores at three different heat shock time points. Trabeculae phenotype is rescued significantly by hsp:GATA3-EGFP at 24 and 26 hpf. Phenotypes are also rescued at 28 hpf, but to a lesser degree as the overall phenotype is not as severe. A two way ANOVA was performed with Holm-Sidak’s multiple comparisons test. At all heat shock timepoints the hsp:DN-BmpR1a controls had significantly worse phenotype when compared to the hsp:DN-BmpR1a;hsp:GATA3-EGFP double heat shock.

Figure Data

Phenotype details

Acknowledgments

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