TDP-43 BiFC can be detected in muscle cells and motor neurons and is predominantly nuclear. a A representative image of a 24 hpf embryo injected with our TDP-43 BiFC constructs. Scale bar, 200 μm. b Fluorescent intensity as a percentage of signal at 24 hpf. c, d Representative pictures of the human wild-type TDP-43 BiFC signal at 24 hpf in muscle cells (c) and spinal cord motor neurons (d). e, f Representative pictures of the human wild-type TDP-43 BiFC signal at 48 hpf in muscle cells (e) and spinal cord motor neurons (f). g, h Representative pictures of the human wild-type TDP-43 BiFC signal at 72 hpf in muscle cells (g) and spinal cord motor neurons (h). Scale bar, 30 μm
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Full text @ Mol. Neurobiol.
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