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Figure 6

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Imle et al., 2019 - ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing

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Figure 6

Adpgk regulates glucose metabolism in zebrafish embryos. (a) Quantification of whole body glucose content and insulin expression in wild type, KD1, and KD2 embryos. N = 6 independent experiments, stage 22 hpf. (b) Ratio of lactate to pyruvate in wild type, KD1, and KD2 embryos. N = 3 independent experiments, stage 22 hpf. (c) Scheme of changes in high mannose glycans, complex- and hybrid-type glycans in KD1 compared to control embryos (stage 22 hpf) analyzed by HILIC-FLR-MS. * p < 0.05, ** p < 0.01, ***p < 0.005.

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