ZFIN Image: Tuttle et al., 2019, Figure 6

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Figure Caption

Figure 6 Sorafenib induces pLLG axon truncation similar to that found in Ret genetic loss-of-function at 72 hpf.

Treatment with 5 μM sorafenib from 24 to 72 hpf induced axon truncations in wild-type siblings (0.50 ± 0.06; n = 44) not significantly different than untreated ret homozygous mutants (0.53 ± 0.03; n = 17; p=0.95 by one way ANOVA with post-hoc Tukey test) or sorafenib-treated ret homozygous mutants (0.50 ± 0.05; n = 16; p=0.92). Error bars represent S.E.M., N.S. = Not significant.

Figure Data

Phenotype details

Acknowledgments

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