ZFIN Image: Neelathi et al., 2018, Fig. 2

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Figure Caption

Fig. 2

Cxcl12a promotes expression of snail1b in the leading domain. (A,B) snail1b expression at the leading end of the primordium in the control embryos (A) and loss of snail1b expression following cxcl12a knockdown (B). (C) snail1b expression at both ends (brackets) following cxcr7b knockdown. (D) Broad snail1b expression in heat-shocked HS:cxcl12a transgenic embryos (HS-cxcl12a). (E,F) snail1b expression in non-heat-shocked transgenics (NO HS-cxcl12a) (E) and in heat-shocked non-transgenic siblings (HS-Sib) (F). (G) cxcl12a induction in the embryo following heat shock-induced expression of cxcl12a in HS:cxcl12a transgenic embryos. (H,I) Lack of cxcl12a induction in non-heat-shocked (H) and in heat-shocked non-transgenic siblings (I). n=20 for each of two independent experiments. Dotted lines encircle pLL primordia.

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Acknowledgments

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