IMAGE

Fig. 3

ID
ZDB-IMAGE-180417-22
Genes
Publication
Rogers et al., 2017 - Nodal patterning without Lefty inhibitory feedback is functional but fragile
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Figures for Rogers et al., 2017
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Figure Caption

Fig. 3

Lefty loss causes expanded expression of mesendodermal genes.

In situ hybridization comparing expression of endodermal (sox32/casanova) (A–E’’’) and mesodermal (noto/floating head) (F–J’’’) genes in wild type, lft1-/- mutants, lft2-/- mutants, and lft1-/-;lft2-/- mutants at the indicated developmental stages (dorsal views). Note upregulation of mesendoderm in lft1-/-;lft2-/- mutants starting at early gastrulation stages (e.g., shield stage). lft1-/-;lft2-/- embryos were generated from lft1+/-;lft2-/- incrosses, lft1-/-;lft2-/- incrosses, or lft1-/-;lft2-/- X lft1+/-;lft2-/- crosses. Embryos were genotyped after imaging (see Materials and methods for details).

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife
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