Gene

noto

ID
ZDB-GENE-990415-75
Name
notochord homeobox
Symbol
noto Nomenclature History
Previous Names
  • Znot
  • flh
  • floating head
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; axial mesoderm morphogenesis; and floor plate formation. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; forebrain; germ ring; mesoderm; and tail bud. Orthologous to human NOTO (notochord homeobox).
Genome Resources
Note
None
Expression
All Expression Data
117 figures from 90 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
52 figures from 31 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With noto Human Ortholog
No data available
Associated With noto Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily
UniProtKB:Q90461 241
UniProtKB:B8A5N9 241
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations