ZFIN ID: ZDB-GENE-011026-1
Gene Name: SRY-box transcription factor 32
Gene Symbol: sox32    Nomenclature History

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Previous Names: 10J3 (1), 226D7 (1), cas (1), casanova, cb527 (1), CG569 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits DNA binding activity; DNA-binding transcription factor activity; and protein heterodimerization activity. Involved in several processes, including circulatory system development; gastrulation; and regulation of endodermal cell fate specification. Predicted to localize to the nuclear transcription factor complex. Is expressed in several structures, including Kupffer's vesicle; blastoderm; blood island; endoderm; and forerunner cell group.
Genome Resources: Alliance (1),  Gene:116990 (1),  Ensembl(GRCz11):ENSDARG00000100591 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s4 Point Mutation Unknown Missense ENU
sa9225 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sox32_unspecified Unspecified Unknown Unknown
    ta56 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 36 figures from 24 publications
    Observed in:
    DISEASE ASSOCIATED WITH sox32 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sox32 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endoderm formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 28)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR009071 High mobility group box domain
    Homologous_superfamily IPR036910 High mobility group box domain superfamily
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM sox32
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(C120:sox32-2A-TagBFP,cryaa:Venus) C120cryaa 2Asox32TagBFPVenus Danio rerio 1 1
    Tg(hsp70l:dnsox32,cryaa:Venus) cryaahsp70l sox32Venus Danio rerio 1 2
    Tg(hsp70l:sox32) hsp70l sox32 Danio rerio 1 2
    MARKER RELATIONSHIPS
    sox32 Encodes: [EST] cb527 (1) (order this)
    [cDNA] MGC:114019 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131851 (1)
    Polypeptide UniProtKB:A0A0R4IRI6 (1) 307 aa
    Sequence Clusters UniGene:133216 (1)
    Sequence Information (all 19)
    ORTHOLOGY for sox32 ( Chr: 7 )
    CITATIONS (224)