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Fig. 3
Increased expression of irf7 in 142T−/− embryos and rescue of HSPC defects by irf7 knockdown. (a and b) 142T−/− embryos showed increased expression of irf7 at 4 dpf using WISH and qPCR (mean±s.d., n=3, *P<0.01). (c) Irf7 MO-injected 142T −/− embryos showed the restoration of runx1 expression at 26 and 36 hpf using WISH. The quantification of runx1-positive cells in the AGM was shown in the lower panel (mean±s.d., n=5, *P<0.05).
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