ZFIN Image: Tanaka et al., 2017, Fig. 4

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Figure Caption

Fig. 4

Dkk1b acts downstream of the FGFsignaling pathway to induce the formation of complete head structures and neuroectoderm patterning. Phenotypic representation of (A) uninjected (50/52), (B) FGF8 mRNA-injected (35/52), and (C) FGF8 mRNA and MOdkk1b-injected ichabod embryos at 24 hpf (38/43). Each image represents the expression pattern of otx2 or hoxb1b in (D and E) wild-type embryos, (F and G) uninjected ichabod embryos, (H and I) FGF8 mRNA-injected ichabod embryos, and (J and K) FGF8 mRNA and MOdkk1b-injected ichabod embryos. (D–K) All embryos are shown at 80% epiboly stage in lateral views. Scale bars represent 100 µm.

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Acknowledgments

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Reprinted from Developmental Biology, 424(2), Tanaka, S., Hosokawa, H., Weinberg, E.S., Maegawa, S., Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish, 189-197, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.