ZFIN Image: Yao et al., 2015, Fig. 5

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Figure Caption

Fig. 5

Effects of IGF-I on the expression of kitlga in the presence of db-cAMP (A), forskolin (B), and H89 (C). Cultured zebrafish follicle cells were pretreated with db-cAMP (1.5 mM), forskolin (10 µM), or H89 (10 µM) for 30 min before treatment with IGF-I (50 ng/mL) for 6 h. (D) Interactive effects of the PKA and PI3K-Akt pathways on kitlga expression. Cultured zebrafish follicle cells were treated with H89 (10 µM) and LY294002 (50 µM) alone or in combination for 6 h. The data were normalized to the housekeeping gene ef1a and expressed as a percentage of the control group (mean ± SEM, n = 4). Different letters indicate statistical significance (P < 0.05).

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Expression / Labeling details

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 402, Yao, K., Ge, W., Differential regulation of Kit Ligand A (kitlga) expression in the zebrafish ovarian follicle cells - evidence for the existence of a cyclic adenosine 3', 5' monophosphate-mediated binary regulatory system during folliculogenesis, 21-31, Copyright (2015) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.