ZFIN Image: Kantarci et al., 2016, Fig. 3

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Figure Caption

Fig. 3

Effects of Gsc on later stages of SAG development. (A?F) Cross-sections passing through the utricular sensory epithelium (dorsal up, medial left) in controls, gsc mutants, and hs:gsc embryos showing expression of nrd (A?C) or Isl1 (outlined in orange, D?F). The otic epithelium is outlined in all images. (Magnification: A?F, 640�.) (G?J) Mean and SD of the total number of nrd+ (G and I) or Isl1+ (H and J) cells for the genotypes indicated in the color key at times presented on the x axes. nrd+ cells were counted on serial sections (n = 3?5), and Isl1+ cells were counted on whole mounts for time points between 30 and 48 hpf (n = 10?17) and on serial sections for 53 and 78 hpf (n = 2?3). (K) Means and SD of the total number of Phospho-Histone H3 (pH3)+ cells within the nrd:Gfp+ domain (which marks TA cells) at the indicated times in control and hs:gsc embryos. Embryos were heat shocked at the indicated times. Asterisks indicate statistically significant differences compared with control embryos (P < 0.05).

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA